证据评分
噻菌灵(噻苯哒唑)对旋毛虫病的治疗:证据质量低,有 3 个病例对照研究,用噻菌灵作为驱虫药物治疗旋毛虫病。然而,噻菌灵(噻苯哒唑)由于存在胃肠道和肝毒性,不再被建议用于旋毛虫病的治疗。[62]Watt G, Saisorn S, Jongsakul K, et al. Blinded, placebo-controlled trial of antiparasitic drugs for trichinosis myositis. J Infect Dis. 2000;182:371-374.http://www.ncbi.nlm.nih.gov/pubmed/10882628?tool=bestpractice.com[65]Horstmann RD, Kern P, Volkmer KJ, et al. Observations on mebendazole vs. thiabendazole in the treatment of human trichinellosis. Tropenmed Parasitol. 1982;33:191-194.http://www.ncbi.nlm.nih.gov/pubmed/7135477?tool=bestpractice.com[66]Fourestie V, Bougnoux ME, Ancelle T, et al. Randomized trial of albendazole versus tiabendazole plus flubendazole during an outbreak of human trichinellosis. Parasitol Res. 1988;75:36-41.http://www.ncbi.nlm.nih.gov/pubmed/3060872?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
噻菌灵(噻苯哒唑)对旋毛虫病的治疗:证据质量低,有 3 个病例对照研究,用噻菌灵作为驱虫药物治疗旋毛虫病。然而,噻菌灵(噻苯哒唑)由于存在胃肠道和肝毒性,不再被建议用于旋毛虫病的治疗。[62]Watt G, Saisorn S, Jongsakul K, et al. Blinded, placebo-controlled trial of antiparasitic drugs for trichinosis myositis. J Infect Dis. 2000;182:371-374.http://www.ncbi.nlm.nih.gov/pubmed/10882628?tool=bestpractice.com[65]Horstmann RD, Kern P, Volkmer KJ, et al. Observations on mebendazole vs. thiabendazole in the treatment of human trichinellosis. Tropenmed Parasitol. 1982;33:191-194.http://www.ncbi.nlm.nih.gov/pubmed/7135477?tool=bestpractice.com[66]Fourestie V, Bougnoux ME, Ancelle T, et al. Randomized trial of albendazole versus tiabendazole plus flubendazole during an outbreak of human trichinellosis. Parasitol Res. 1988;75:36-41.http://www.ncbi.nlm.nih.gov/pubmed/3060872?tool=bestpractice.com