伊维菌素
伊维菌素在小鼠的旋毛虫病动物模型中有效,但目前尚未用于人体。[72]el-Azzouni MZ. Effect of ivermectin on experimental trichinosis. J Egypt Soc Parasitol. 1997;27:331-340.http://www.ncbi.nlm.nih.gov/pubmed/9257971?tool=bestpractice.com
依吗德塞
这个八酯肽环药物可以通过阻断蛛毒素样受体来杀死旋毛虫,但目前尚未在人体进行试验。[73]Harder A, Schmitt-Wrede HP, Krucken J, et al. Cyclooctadepsipeptides - an anthelmintically active class of compounds exhibiting a novel mode of action. Int J Antimicrob Agents. 2003;22:318-331.http://www.ncbi.nlm.nih.gov/pubmed/13678839?tool=bestpractice.com
与 HP-βCD 结合的苯并咪唑类药物
2-羟丙基-β-环糊精(HP-β-CD)可以提高小鼠模型体内苯并咪唑类药物的生物利用度,但尚未在人体试验。[74]Casulli A, Morales MA, Gallinella B, et al. 2-Hydroxypropyl-beta-cyclodextrin improves the effectiveness of albendazole against encapsulated larvae of Trichinella spiralis in a murine model. J Antimicrob Chemother. 2006;58:886-890.http://jac.oxfordjournals.org/content/58/4/886.fullhttp://www.ncbi.nlm.nih.gov/pubmed/16895937?tool=bestpractice.com