BMJ Best Practice

证据

  • Can dietary fiber help prevent recurrence of colorectal adenoma and development of carcinoma?
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  • What are the benefits and harms of screening for colorectal cancer (CRC) with the fecal occult blood test, Hemoccult?
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  • How do flexible sigmoidoscopy and fecal occult blood tests compare with each other and no screening for detecting colorectal cancer in asymptomatic adults?
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  • What are the effects of Enhanced Recovery after Surgery (ERAS) compared with conventional recovery strategies in people undergoing colorectal surgery?
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  • What are the effects of epidermal growth factor receptor inhibitor monoclonal antibodies for people with KRAS exon 2 genotype metastatic colorectal cancer?
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  • Is there randomized controlled trial evidence to support the use of postoperative adjuvant chemotherapy in people with rectal cancer operated for cure?
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  • How does second-line irinotecan-based combination therapy compare with irinotecan alone in people with metastatic colorectal cancer?
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  • Can adding targeted therapy to second-line systemic chemotherapy improve outcomes in people with metastatic colorectal cancer?
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