BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 疲乏/不适感
  • 厌食
  • 腹部不适

其他诊断因素

  • 瘙痒
  • 关节痛
  • 恶心
  • 发热

危险因素

  • 女性
  • 遗传易感性
  • 免疫失调
  • 麻疹病毒

诊断性检查

首要检查

  • 天冬氨酸转氨酶
  • 丙氨酸氨基转移酶
  • 胆红素
  • γ-GT
全部具体信息

需要考虑的检查

  • ANA(抗核抗体)
  • SMA(平滑肌抗体)
  • 抗-SLA/LP(抗可溶性肝抗原或肝/胰腺)
  • p-ANCA(核周抗中性粒细胞胞质抗体)
全部具体信息

新兴检查

  • AAA(抗肌动蛋白抗体)
  • 抗-ASGP-R(去唾液酸蛋白受体抗体)
全部具体信息

治疗流程

贡献者

George Y. Wu MD, PhD

Professor of Medicine

University of Connecticut School of Medicine

Farmington

CT

利益冲突披露
GYW is on the medical advisory boards of Gilead Sciences, Inc; Bristol-Myers Squibb, Inc; Abbvie, Inc; and Intercept, Inc.
Roopjeet K. Bath MBBS

Gastroenterology/Hepatology Fellow

University of Connecticut School of Medicine

Farmington

CT

利益冲突披露
RKB declares that she has no competing interests.

Dr George Y. Wu and Dr Roopjeet K. Bath would like to gratefully acknowledge Dr Micheal Tadros, Dr Lucija Virovic Jukic, Dr Marcy L. Coash, and Dr Deepika Devuni, previous contributors to this monograph. Dr Wu would also like to acknowledge the assistance of Dr Nathan Selky in the 2011 update. MT, LVJ, MLC, and DD declare that they have no competing interests.

Assistant Professor

Division of Gastroenterology

Department of Medicine

Brown University

RI

利益冲突披露
KP declares that he has no competing interests.

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