高压氧
据报告，高压氧治疗作为抗生素治疗的辅助治疗可以减少永久性残疾。[53]Ravicovitch MA, Spallone A. Spinal epidural abscesses: surgical and parasurgical management. Eur Neurol. 1982;21:347-357.http://www.ncbi.nlm.nih.gov/pubmed/7117323?tool=bestpractice.com[54]Chang WC, Tsou HK, Kao TH, et al. Successful treatment of extended epidural abscess and long segment osteomyelitis: a case report and review of the literature. Surg Neurol. 2008;69:117-120.http://www.ncbi.nlm.nih.gov/pubmed/17825364?tool=bestpractice.com然而，这种治疗方法仍然是不常使用。
微创手术
对于需要手术干预的患者，正在研究胸腔镜和椎间孔镜技术的发展能否减少术后脊柱不稳定性。[55]Muckley T, Schutz T, Schmidt MH, et al. The role of thoracoscopic spinal surgery in the management of pyogenic vertebral osteomyelitis. Spine. 2004;29:E227-E233.http://www.ncbi.nlm.nih.gov/pubmed/15167673?tool=bestpractice.com
辅助性局部抗生素
可以向感染部位快速输送抗生素的新型局部抗生素输送系统的应用正在研究中。[42]Wang J, Calhoun JH, Mader JT. The application of bioimplants in the management of chronic osteomyelitis. Orthopedics. 2002;25:1247-1252.http://www.ncbi.nlm.nih.gov/pubmed/12452341?tool=bestpractice.com[56]Jackson SR, Richelsoph KC, Courtney HS, et al. Preliminary in vitro evaluation of an adjunctive therapy for extremity wound infection reduction: rapidly resorbing local antibiotic delivery. J Orthop Res. 2009;27:903-908.http://www.ncbi.nlm.nih.gov/pubmed/19105225?tool=bestpractice.com[57]Yarboro SR, Baum EJ, Dahners LE. Locally administered antibiotics for prophylaxis against surgical wound infection: an in vivo study. J Bone Joint Surg Am. 2007;89:929-933.http://www.ncbi.nlm.nih.gov/pubmed/17473127?tool=bestpractice.com
