BMJ Best Practice

证据

  • How effective and safe is amitriptyline for treatment of adults with fibromyalgia?
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  • What are the benefits and harms of serotonin and noradrenaline reuptake inhibitors (SNRIs) in people with fibromyalgia syndrome?
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  • In people with fibromyalgia, how do anticonvulsants affect outcomes?
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  • Does milnacipran improve pain in adults with fibromyalgia?
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  • What are the effects of recommended doses of pregabalin given for pain relief to people with fibromyalgia?
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  • In people with fibromyalgia, how do psychological therapies affect outcomes?
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  • In people with fibromyalgia, what are the effects of cognitive behavioral therapies?
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  • In people with fibromyalgia, is there randomized controlled trial evidence to support the use of resistance exercise training?
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证据评分

    证据 A

    改善纤维肌痛患者的睡眠差和疼痛：有高质量的证据表明，在运动和/或 CBT 的基础上加用三环类抗抑郁药可能对有睡眠障碍和持久疼痛的纤维肌痛患者有益。[61][60][62]

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