BMJ Best Practice
最后审核时间: 一月 2019
最近更新时间: 十一月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 咳嗽
  • 呼吸困难
  • 咯血

其他诊断因素

  • 男性
  • 疲劳
  • 肺部检查异常
  • 男性

危险因素

  • 吸烟
  • 暴露于烟草环境
  • 慢性阻塞性肺疾病
  • 家族史

诊断性检查

首要检查

  • 胸部 X 线检查
  • 颈部下段、胸部和上腹部的对比增强 CT 检查
全部具体信息

需要考虑的检查

  • 痰液细胞学检查
  • 支气管镜检查
  • 活检
  • 具有诊断意义的胸腔穿刺术和/或胸膜活检
全部具体信息

新兴检查

  • 程序性死亡-配体 1 (PD-L1) 检测
  • BRAF 检测
全部具体信息

治疗流程

贡献者

Consultant Respiratory Physician

Nottingham University Hospitals

Honorary Professor of Medicine

University of Nottingham

Respiratory Medicine Unit

David Evans Research Centre

City Hospital Campus

Nottingham

UK

利益冲突披露
DRB has received a lecture fee from Pierre-Fabre and educational grants from Boehringer Ingelheim Ltd, Irwin Mitchell, Roche, and Siemans; DRB has received assistance for travel to an international meeting from OncImmune Ltd.

Consultant Medical Oncologist

Department of Medicine

Royal Marsden Hospital

London

UK

利益冲突披露
SP has been paid as a consultant to Eli Lilly and has acted as consultant to AstraZeneca, Boehringer Ingelheim, Clovis Oncology, BMS, MSD, Pfizer, Novartis, and Ariad. SP has received research grants from Pierre Fabre, Otsuka, and Boehringer Ingelheim. SP has received assistance for travel from Boehringer Ingelheim, MSD, and Pfizer.

Professor David R. Baldwin and Dr Sanjay Popat would like to gratefully acknowledge Dr Mick Peake, Dr Chris Kelsey, and Dr Lawrence Marks, previous contributors to this topic. MP has received lecture fees: AstraZeneca Pharmaceuticals, Lilly Oncology Ltd, Pierre-Fabre, GSK Ltd, and Roche Pharmaceuticals Ltd. MP has also received educational grants to attend scientific conferences from Roche Pharmaceuticals Ltd and Boehringer Ingelheim Ltd. CK and LM declare that they have no competing interests.

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Professor

Assistant Dean

Undergraduate Program

McMaster University

Hamilton

Ontario

Canada

利益冲突披露
AN declares that he has no competing interests.

Assistant Attending Surgeon

Thoracic Service

Memorial Sloan Kettering Cancer Center

New York

NY

利益冲突披露
JH declares that he has no competing interests.

Consultant Medical Oncologist

University College Hospital

London

UK

利益冲突披露
SML declares that he has no competing interests.

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