BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 分钟通气量增加
  • 核心体温升高
  • 肌强直

其他诊断因素

  • 心动过速
  • 尿量减少
  • 心动过速
  • 尿量减少

危险因素

  • 暴露于强效吸入麻醉剂和/或琥珀(琥珀胆碱)
  • 易患 MH
  • 以前的 MH 发作
  • 阳性家族史

诊断性检查

首要检查

  • 终止吸入麻醉
  • 呼出的二氧化碳、氧和耗氧量
  • 静脉血气
  • 血清电解质
全部具体信息

需要考虑的检查

  • 咖啡因氟烷挛缩试验 (CHCT)
  • 体外挛缩试验 (IVCT)
  • 基因检测
  • 肌酶缺陷筛查
全部具体信息

治疗流程

贡献者

Assistant Professor

Department of Anesthesiology

University of Colorado

Aurora

CO

利益冲突披露
LM declares that she has no competing interests.

Professor

Department of Anesthesiology

University of Pittsburgh School of Medicine

Pittsburgh

PA

利益冲突披露
BWB has been reimbursed by the not-for-profit sponsor of the North American MH Registry (NAMHR), the Malignant Hyperthermia Association of the United States (MHAUS) for attending meetings related to the management of the NAMHR. For the past 16 years, BWB received grants from MHAUS to maintain the NAMHR. BWB has given lectures and prepared educational materials for her previous employer, the Department of Anesthesiology in the University of Pittsburgh. As of 1 July, 2016, BWB retired from that employment. BWB has published papers and prepared educational materials for MHAUS, with the help of other volunteers for MHAUS. BWB sponsored LM for an award granted by the American Society of Anesthesiologists. This award allowed LM to travel to several medical centers that were active in the diagnosis of MH, as well as to the NAMHR to improve her understanding of this syndrome. This is part of BWB's mentoring of younger anesthesiologists. BWB is also an author of a number of references cited in this topic.

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Director

Department of Medical Education and Clinical Research

Saint Barnabas Medical Center

Livingstone

NJ

利益冲突披露
HR declares that he has no competing interests.

Professor of Anesthesia

University of Leeds

Academic Unit of Anesthesia

St James's University Hospital

Leeds

UK

利益冲突披露
PH is an author of a number of references cited in this monograph.

Associate Professor

Perioperative Patient Safety

Department of Biomedicine

University Hospital Basel

Basel

Switzerland

利益冲突披露
TG declares that he has no competing interests.

Professor and Chairman

Department of Anesthesiology

Wake Forest University School of Medicine

Winston-Salem

NC

利益冲突披露
JT is an author of a number of references cited in this monograph.

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