癣菌感染的预后好。但免疫抑制的患者可能持续感染或者发展为侵入性真菌感染。
甲癣是最难治的真菌感染,治疗失败率为20%-40%,[45]Sigurgeirsson B, Olafsson JH, Steinsson JB, et al. Long-term effectiveness of treatment with terbinafine vs. itraconazole in onychomycosis: a 5-year blinded prospective follow-up study. Arch Dermatol. 2002;138:353-357.http://www.ncbi.nlm.nih.gov/pubmed/11902986?tool=bestpractice.com复发率或再感染率为20%-50%。[46]Scher RK, Baran R. Onychomycosis in clinical practice: factors contributing to recurrence. Br J Dermatol. 2003;149(suppl 65):5-9.http://www.ncbi.nlm.nih.gov/pubmed/14510969?tool=bestpractice.com 故治疗期和结束后也需间隔数月复诊。