激光治疗和光治疗
一些激光疗法和光疗法已用于痤疮治疗。最著名的光疗法是蓝光疗法,用来靶向治疗痤疮丙酸杆菌。但是,该技术治疗产生了不一致的结果。[52]Tzung TY, Wu KH, Huang ML. Blue light phototherapy in the treatment of acne. Photodermatol Photoimmunol Photomed. 2004;20:266-269.http://www.ncbi.nlm.nih.gov/pubmed/15379878?tool=bestpractice.com[53]Kawada A, Aragane Y, Kameyama H, et al. Acne phototherapy with a high-intensity, enhanced, narrow-band, blue light source: an open study and in vitro investigation. J Dermatol Sci. 2002;30:129-135.http://www.ncbi.nlm.nih.gov/pubmed/12413768?tool=bestpractice.com[54]Riddle CC, Terrell SN, Menser MB, et al. A review of photodynamic therapy (PDT) for the treatment of acne vulgaris. J Drugs Dermatol. 2009;8:1010-1019.http://www.ncbi.nlm.nih.gov/pubmed/19894368?tool=bestpractice.com 运用脉冲染料激光疗法也产生了不一致的结果。[55]Seaton E, Charakida A, Mouser P, et al. Pulsed-dye laser treatment for inflammatory acne vulgaris: randomized controlled trial. Lancet. 2003;362:1347-1352.http://www.ncbi.nlm.nih.gov/pubmed/14585635?tool=bestpractice.com[56]Orringer JS, Kang S, Hamilton T, et al. Treatment of acne vulgaris with a pulsed dye laser: a randomized controlled trial. JAMA. 2004;291:2834-2839.http://www.ncbi.nlm.nih.gov/pubmed/15199033?tool=bestpractice.com 这些疗法仍非常规疗法,需要更多研究来评估其有效性并确定长期不良反应。[57]Haedersdal M, Togsverd-Bo K, Wulf HC. Evidence-based review of lasers, light sources and photodynamic therapy in the treatment of acne vulgaris. J Eur Acad Dermatol Venereol. 2008;22:267-278.http://www.ncbi.nlm.nih.gov/pubmed/18221341?tool=bestpractice.com[58]Hamilton FL, Car J, Lyons C, et al. Laser and other light therapies for the treatment of acne vulgaris: systematic review. Br J Dermatol. 2009;160:1273-1285.http://www.ncbi.nlm.nih.gov/pubmed/19239470?tool=bestpractice.com 有一些激光疗法(剥脱治疗和非剥脱治疗)可用来治疗残留痤疮瘢痕。[59]Ong MW, Bashir SJ. Fractional laser resurfacing for acne scars: a review. Br J Dermatol. 2012;166:1160-1169.http://www.ncbi.nlm.nih.gov/pubmed/22296284?tool=bestpractice.com