有些肠绞痛婴儿对大分子的肠道通透性增高;这反映了胃肠道的功能不成熟,并导致获得性食物过敏。[19]Lothe L, Lindberg T, Jakobsson I. Macromolecular absorption in infants with infantile colic. Acta Paediatr Scand. 1990;79:417-421.http://www.ncbi.nlm.nih.gov/pubmed/2349878?tool=bestpractice.com
婴儿肠绞痛与胃动素水平升高有关。[12]Shenassa ED, Brown MJ. Maternal smoking and infantile gastrointestinal dysregulation: the case of colic. Pediatrics. 2004;114:e497-e505.http://www.ncbi.nlm.nih.gov/pubmed/15466076?tool=bestpractice.com[19]Lothe L, Lindberg T, Jakobsson I. Macromolecular absorption in infants with infantile colic. Acta Paediatr Scand. 1990;79:417-421.http://www.ncbi.nlm.nih.gov/pubmed/2349878?tool=bestpractice.com胃动素刺激胃肠道蠕动,胃动素水平高可导致肠痉挛。药草暴露与血浆和肠道胃动素水平增高相关。[12]Shenassa ED, Brown MJ. Maternal smoking and infantile gastrointestinal dysregulation: the case of colic. Pediatrics. 2004;114:e497-e505.http://www.ncbi.nlm.nih.gov/pubmed/15466076?tool=bestpractice.com
也有证据证明婴儿肠绞痛中胆囊收缩力降低。[20]Lehtonen L, Svedstrom E, Korvenranta H. Gallbladder hypocontractility in infantile colic. Acta Paediatr. 1994;83:1174-1177.http://www.ncbi.nlm.nih.gov/pubmed/7841734?tool=bestpractice.com收缩力过低可能是由于胆囊收缩素分泌紊乱。