中耳炎

• In children with acute otitis media, what are the effects of antibiotics?
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• In children and adolescents with acute otitis media, how do topical anesthetic ear drops affect outcomes?
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• In children up to 12 years of age, what are the benefits and harms of xylitol for preventing acute otitis media?
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• In children at high risk of acute and chronic suppurative otitis media, is there randomized controlled trial evidence to support the use of antibiotic prophylaxis?
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证据评分

证据 C 抗生素疗法选择：有较差质量证据表明，阿莫西林或阿莫西林/克拉维酸在减轻急性中耳炎体征和症状方面比大环内酯类或头孢菌素更有效，而其他抗生素的疗效彼此相当。 系统评价或者受试者＞200名的随机对照临床试验（RCT）。

抗生素疗法选择：有较差质量证据表明，阿莫西林或阿莫西林/克拉维酸在减轻急性中耳炎体征和症状方面比大环内酯类或头孢菌素更有效，而其他抗生素的疗效彼此相当。