不论其症状如何,患者均需接受积极的危险因素干预。[2]Gerhard-Herman MD, Gornik HL, Barrett C, et al. 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: executive summary. Circulation. 2017 Mar 21;135(12):e686-e725.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479414/http://www.ncbi.nlm.nih.gov/pubmed/27840332?tool=bestpractice.com由于 PAD 患者心血管事件的发病率和死亡率均明显增加,因此对心血管危险因素进行干预至关重要。危险因素干预包括控制血压、糖尿病、血脂及戒烟。[2]Gerhard-Herman MD, Gornik HL, Barrett C, et al. 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: executive summary. Circulation. 2017 Mar 21;135(12):e686-e725.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479414/http://www.ncbi.nlm.nih.gov/pubmed/27840332?tool=bestpractice.com