BMJ Best Practice

证据

  • How do different oral 5-aminosalicylic acid regimens compare for maintenance of remission in people with ulcerative colitis?
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  • Is there randomized controlled trial evidence to support the use of etrolizumab for induction of remission in people with ulcerative colitis?
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  • Is there randomized controlled trial evidence to support the use of probiotics for the maintenance of remission in people with ulcerative colitis?
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  • How does surveillance compare with no surveillance for detecting colon cancer in people with ulcerative colitis or inflammatory bowel disease?
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证据评分

    证据 A

    缓解、黏膜愈合和需用结肠切除手术：高质量的研究证明英夫利昔单抗可有效诱导临床缓解，并促进黏膜愈合，对那些常规治疗难治性的中重度炎症性结肠炎患者，可在短期减少结肠切除术需求。而且现已证明，作为挽救治疗，可有效诱导缓解。在治疗中重度溃疡性结肠炎方面，比安慰剂更为有效。[56][57][58][59][60][61]

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