证据评分
鳞状细胞癌的发病率:中等质量证据证实日常应用防晒霜相较于随意使用防晒霜或安慰剂,每日使用防晒霜能更有效地降低鳞状细胞癌发病率和新发日光角化症的风险。[10]Lin JS, Eder M, Weinmann S. Behavioral counseling to prevent skin cancer: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2011;154:190-201.http://www.ncbi.nlm.nih.gov/pubmed/21282699?tool=bestpractice.com[11]Green A, Williams G, Neale R, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinoma of the skin: a randomised controlled trial. Lancet. 1999;345:723-729.http://www.ncbi.nlm.nih.gov/pubmed/10475183?tool=bestpractice.com[12]Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med. 1993;329:1147-1151.http://www.nejm.org/doi/full/10.1056/NEJM199310143291602#t=articleTophttp://www.ncbi.nlm.nih.gov/pubmed/8377777?tool=bestpractice.com[13]Darlington S, Williams G, Neale R, et al. A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses. Arch Dermatol. 2003;139:451-455.http://archderm.ama-assn.org/cgi/content/full/139/4/451http://www.ncbi.nlm.nih.gov/pubmed/12707092?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
鳞状细胞癌的发病率:中等质量证据证实日常应用防晒霜相较于随意使用防晒霜或安慰剂,每日使用防晒霜能更有效地降低鳞状细胞癌发病率和新发日光角化症的风险。[10]Lin JS, Eder M, Weinmann S. Behavioral counseling to prevent skin cancer: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2011;154:190-201.http://www.ncbi.nlm.nih.gov/pubmed/21282699?tool=bestpractice.com[11]Green A, Williams G, Neale R, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinoma of the skin: a randomised controlled trial. Lancet. 1999;345:723-729.http://www.ncbi.nlm.nih.gov/pubmed/10475183?tool=bestpractice.com[12]Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med. 1993;329:1147-1151.http://www.nejm.org/doi/full/10.1056/NEJM199310143291602#t=articleTophttp://www.ncbi.nlm.nih.gov/pubmed/8377777?tool=bestpractice.com[13]Darlington S, Williams G, Neale R, et al. A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses. Arch Dermatol. 2003;139:451-455.http://archderm.ama-assn.org/cgi/content/full/139/4/451http://www.ncbi.nlm.nih.gov/pubmed/12707092?tool=bestpractice.com